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Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition
Methylation of the small ribosome subunit rRNA in the ribosomal decoding center results in exceptionally high-level aminoglycoside resistance in bacteria. Enzymes that methylate 16S rRNA on N7 of nucleotide G1405 (m(7)G1405) have been identified in both aminoglycoside-producing and clinically drug-r...
में बचाया:
| में प्रकाशित: | J Biol Chem |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6873201/ https://ncbi.nlm.nih.gov/pubmed/31594862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011181 |
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