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Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis
The pregnane X receptor (PXR) is a nuclear receptor (NR), involved in the detoxification of xenobiotic compounds. Recently, its presence was reported in the human vasculature and its ligands were proposed to exhibit anti-atherosclerotic effects. Since platelets contribute towards the development of...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868193/ https://ncbi.nlm.nih.gov/pubmed/31748641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53218-x |
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