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Detecting association of rare and common variants by adaptive combination of P-values
Genome-wide association studies (GWAS) can detect common variants associated with diseases. Next generation sequencing technology has made it possible to detect rare variants. Most of association tests, including burden tests and nonburden tests, mainly target rare variants by upweighting rare varia...
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| Yayımlandı: | Genet Res (Camb) |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cambridge University Press
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863635/ https://ncbi.nlm.nih.gov/pubmed/26440553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0016672315000208 |
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