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Association analysis of rare and common variants with multiple traits based on variable reduction method
Pleiotropy, the effect of one variant on multiple traits, is widespread in complex diseases. Joint analysis of multiple traits can improve statistical power to detect genetic variants and uncover the underlying genetic mechanism. Currently, a large number of existing methods target one common varian...
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| Publicado en: | Genet Res (Camb) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cambridge University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6865155/ https://ncbi.nlm.nih.gov/pubmed/29386084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0016672317000052 |
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