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Association analysis of rare and common variants with multiple traits based on variable reduction method

Pleiotropy, the effect of one variant on multiple traits, is widespread in complex diseases. Joint analysis of multiple traits can improve statistical power to detect genetic variants and uncover the underlying genetic mechanism. Currently, a large number of existing methods target one common varian...

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Detalhes bibliográficos
Publicado no:Genet Res (Camb)
Main Authors: CHEN, LILI, WANG, YONG, ZHOU, YAJING
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6865155/
https://ncbi.nlm.nih.gov/pubmed/29386084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0016672317000052
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