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Testing an optimally weighted combination of common and/or rare variants with multiple traits

Recently, joint analysis of multiple traits has become popular because it can increase statistical power to identify genetic variants associated with complex diseases. In addition, there is increasing evidence indicating that pleiotropy is a widespread phenomenon in complex diseases. Currently, most...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Wang, Zhenchuan, Sha, Qiuying, Fang, Shurong, Zhang, Kui, Zhang, Shuanglin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062080/
https://ncbi.nlm.nih.gov/pubmed/30048520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201186
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