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Testing an optimally weighted combination of common and/or rare variants with multiple traits

Recently, joint analysis of multiple traits has become popular because it can increase statistical power to identify genetic variants associated with complex diseases. In addition, there is increasing evidence indicating that pleiotropy is a widespread phenomenon in complex diseases. Currently, most...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Zhenchuan, Sha, Qiuying, Fang, Shurong, Zhang, Kui, Zhang, Shuanglin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062080/
https://ncbi.nlm.nih.gov/pubmed/30048520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201186
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