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Testing an optimally weighted combination of common and/or rare variants with multiple traits

Recently, joint analysis of multiple traits has become popular because it can increase statistical power to identify genetic variants associated with complex diseases. In addition, there is increasing evidence indicating that pleiotropy is a widespread phenomenon in complex diseases. Currently, most...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wang, Zhenchuan, Sha, Qiuying, Fang, Shurong, Zhang, Kui, Zhang, Shuanglin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062080/
https://ncbi.nlm.nih.gov/pubmed/30048520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201186
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