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A General Statistic to Test an Optimally Weighted Combination of Common and/or Rare Variants

Both genome-wide association study and next generation sequencing data analyses are widely employed in order to identify disease susceptible common and/or rare genetic variants. Rare variants generally have large effects though they are hard to detect due to their low frequencies. Currently, many ex...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Zhang, Jianjun, Wu, Baolin, Sha, Qiuying, Zhang, Shuanglin, Wang, Xuexia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829034/
https://ncbi.nlm.nih.gov/pubmed/31498476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22255
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