Testing optimally weighted combination of variants for hypertension

Testing rare variants directly is possible with next-generation sequencing technology. In this article, we propose a sliding-window-based optimal-weighted approach to test for the effects of both rare and common variants across the whole genome. We measured the genetic association between a disease...

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Bibliographic Details
Main Authors: Zhao, Xingwang, Sha, Qiuying, Zhang, Shuanglin, Wang, Xuexia
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Proceedings
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143713/
https://ncbi.nlm.nih.gov/pubmed/25519394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S59
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