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Detecting Association of Rare Variants by Testing an Optimally Weighted Combination of Variants for Quantitative Traits in General Families

Although next-generation sequencing technology allows sequencing the whole genome of large groups of individuals, the development of powerful statistical methods for rare variant association studies is still underway. Even though many statistical methods have been developed for mapping rare variants...

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Detalhes bibliográficos
Main Authors: Fang, Shurong, Zhang, Shuanglin, Sha, Qiuying
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932153/
https://ncbi.nlm.nih.gov/pubmed/23968488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12038
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