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Testing rare variants for hypertension using family-based tests with different weighting schemes

Next-generation sequencing technology makes directly testing rare variants possible. However, existing statistical methods to detect common variants may not be optimal for testing rare variants because of allelic heterogeneity as well as the extreme rarity of individual variants. Recently, several s...

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Dades bibliogràfiques
Publicat a:BMC Proc
Autors principals: Wang, Xuexia, Zhao, Xingwang, Zhou, Jin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133509/
https://ncbi.nlm.nih.gov/pubmed/27980642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0036-7
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