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Testing rare variants for hypertension using family-based tests with different weighting schemes

Next-generation sequencing technology makes directly testing rare variants possible. However, existing statistical methods to detect common variants may not be optimal for testing rare variants because of allelic heterogeneity as well as the extreme rarity of individual variants. Recently, several s...

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Библиографические подробности
Опубликовано в: :BMC Proc
Главные авторы: Wang, Xuexia, Zhao, Xingwang, Zhou, Jin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133509/
https://ncbi.nlm.nih.gov/pubmed/27980642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0036-7
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