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Adjustment of familial relatedness in association test for rare variants

High-throughput sequencing technology allows researchers to test associations between phenotypes and all the variants identified throughout the genome, and is especially useful for analyzing rare variants. However, the statistical power to identify phenotype-associated rare variants is very low with...

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Bibliographic Details
Main Authors: Li, Cong, Yang, Can, Chen, Mengjie, Chen, Xiaowei, Hou, Lin, Zhao, Hongyu
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143885/
https://ncbi.nlm.nih.gov/pubmed/25519384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S39
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