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Adjustment of familial relatedness in association test for rare variants
High-throughput sequencing technology allows researchers to test associations between phenotypes and all the variants identified throughout the genome, and is especially useful for analyzing rare variants. However, the statistical power to identify phenotype-associated rare variants is very low with...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143885/ https://ncbi.nlm.nih.gov/pubmed/25519384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S39 |
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