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Adjustment of familial relatedness in association test for rare variants

High-throughput sequencing technology allows researchers to test associations between phenotypes and all the variants identified throughout the genome, and is especially useful for analyzing rare variants. However, the statistical power to identify phenotype-associated rare variants is very low with...

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Detalhes bibliográficos
Main Authors: Li, Cong, Yang, Can, Chen, Mengjie, Chen, Xiaowei, Hou, Lin, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143885/
https://ncbi.nlm.nih.gov/pubmed/25519384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S39
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