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Adjustment of familial relatedness in association test for rare variants

High-throughput sequencing technology allows researchers to test associations between phenotypes and all the variants identified throughout the genome, and is especially useful for analyzing rare variants. However, the statistical power to identify phenotype-associated rare variants is very low with...

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Bibliografiske detaljer
Main Authors: Li, Cong, Yang, Can, Chen, Mengjie, Chen, Xiaowei, Hou, Lin, Zhao, Hongyu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143885/
https://ncbi.nlm.nih.gov/pubmed/25519384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S39
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