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Adjustment of familial relatedness in association test for rare variants

High-throughput sequencing technology allows researchers to test associations between phenotypes and all the variants identified throughout the genome, and is especially useful for analyzing rare variants. However, the statistical power to identify phenotype-associated rare variants is very low with...

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Bibliografske podrobnosti
Main Authors: Li, Cong, Yang, Can, Chen, Mengjie, Chen, Xiaowei, Hou, Lin, Zhao, Hongyu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143885/
https://ncbi.nlm.nih.gov/pubmed/25519384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S39
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