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Testing rare variants for hypertension using family-based tests with different weighting schemes

Next-generation sequencing technology makes directly testing rare variants possible. However, existing statistical methods to detect common variants may not be optimal for testing rare variants because of allelic heterogeneity as well as the extreme rarity of individual variants. Recently, several s...

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Detalhes bibliográficos
Publicado no:BMC Proc
Main Authors: Wang, Xuexia, Zhao, Xingwang, Zhou, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133509/
https://ncbi.nlm.nih.gov/pubmed/27980642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0036-7
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