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Detecting association of rare and common variants by adaptive combination of P-values
Genome-wide association studies (GWAS) can detect common variants associated with diseases. Next generation sequencing technology has made it possible to detect rare variants. Most of association tests, including burden tests and nonburden tests, mainly target rare variants by upweighting rare varia...
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| Publicado no: | Genet Res (Camb) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cambridge University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863635/ https://ncbi.nlm.nih.gov/pubmed/26440553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0016672315000208 |
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