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Adaptive clustering and adaptive weighting methods to detect disease associated rare variants

Current statistical methods to test association between rare variants and phenotypes are essentially the group-wise methods that collapse or aggregate all variants in a predefined group into a single variant. Comparing with the variant-by-variant methods, the group-wise methods have their advantages...

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Detalhes bibliográficos
Main Authors: Sha, Qiuying, Wang, Shuaicheng, Zhang, Shuanglin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573192/
https://ncbi.nlm.nih.gov/pubmed/22781093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.143
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