Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

Although correlations between RNA polymerase II (RNAPII) transcription stress, R-loops, and genome instability have been established, the mechanisms underlying these connections remain poorly understood. Here, we used a mutant version of the transcription elongation factor TFIIS (TFIIS(mut)), aiming...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Zatreanu, Diana, Han, Zhong, Mitter, Richard, Tumini, Emanuela, Williams, Hannah, Gregersen, Lea, Dirac-Svejstrup, A. Barbara, Roma, Stefania, Stewart, Aengus, Aguilera, Andres, Svejstrup, Jesper Q.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863433/
https://ncbi.nlm.nih.gov/pubmed/31519522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.037
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller