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RECQL5 Controls Transcript Elongation and Suppresses Genome Instability Associated with Transcription Stress
RECQL5 is the sole member of the RECQ family of helicases associated with RNA polymerase II (RNAPII). We now show that RECQL5 is a general elongation factor that is important for preserving genome stability during transcription. Depletion or overexpression of RECQL5 results in corresponding shifts i...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032574/ https://ncbi.nlm.nih.gov/pubmed/24836610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.048 |
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