Caricamento...

RECQL5 Controls Transcript Elongation and Suppresses Genome Instability Associated with Transcription Stress

RECQL5 is the sole member of the RECQ family of helicases associated with RNA polymerase II (RNAPII). We now show that RECQL5 is a general elongation factor that is important for preserving genome stability during transcription. Depletion or overexpression of RECQL5 results in corresponding shifts i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Saponaro, Marco, Kantidakis, Theodoros, Mitter, Richard, Kelly, Gavin P., Heron, Mark, Williams, Hannah, Söding, Johannes, Stewart, Aengus, Svejstrup, Jesper Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032574/
https://ncbi.nlm.nih.gov/pubmed/24836610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.048
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !