UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene

The transcription-related DNA damage response was analyzed on a genome-wide scale with great spatial and temporal resolution. Upon UV irradiation, a slowdown of transcript elongation and restriction of gene activity to the promoter-proximal ∼25 kb is observed. This is associated with a shift from ex...

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Publicat a:Cell
Autors principals: Williamson, Laura, Saponaro, Marco, Boeing, Stefan, East, Philip, Mitter, Richard, Kantidakis, Theodoros, Kelly, Gavin P., Lobley, Anna, Walker, Jane, Spencer-Dene, Bradley, Howell, Michael, Stewart, Aengus, Svejstrup, Jesper Q.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332558/
https://ncbi.nlm.nih.gov/pubmed/28215706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.01.019
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