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The Cellular Response to Transcription-Blocking DNA Damage
In response to transcription-blocking DNA lesions such as those generated by UV irradiation, cells activate a multipronged DNA damage response. This response encompasses repair of the lesions that stall RNA polymerase (RNAP) but also a poorly understood, genome-wide shutdown of transcription, even o...
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Publicado no: | Trends Biochem Sci |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Trends Journals
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929563/ https://ncbi.nlm.nih.gov/pubmed/29699641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.02.010 |
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