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The Cellular Response to Transcription-Blocking DNA Damage

In response to transcription-blocking DNA lesions such as those generated by UV irradiation, cells activate a multipronged DNA damage response. This response encompasses repair of the lesions that stall RNA polymerase (RNAP) but also a poorly understood, genome-wide shutdown of transcription, even o...

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Bibliografski detalji
Izdano u:Trends Biochem Sci
Glavni autori: Gregersen, Lea H., Svejstrup, Jesper Q.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Trends Journals 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929563/
https://ncbi.nlm.nih.gov/pubmed/29699641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.02.010
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