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The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

Shortening of poly(A) tails triggers mRNA degradation; hence, mRNA deadenylation regulates many biological events. In the present study, we generated mice lacking the Cnot1 gene, which encodes an essential scaffold subunit of the CCR4–NOT deadenylase complex in adipose tissues (Cnot1-AKO mice) and w...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Takahashi, Akinori, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Ferwati, Sara, Kuba, Keiji, Yamamoto, Tadashi, Suzuki, Toru
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862216/
https://ncbi.nlm.nih.gov/pubmed/31652943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215274
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