The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

Shortening of poly(A) tails triggers mRNA degradation; hence, mRNA deadenylation regulates many biological events. In the present study, we generated mice lacking the Cnot1 gene, which encodes an essential scaffold subunit of the CCR4–NOT deadenylase complex in adipose tissues (Cnot1-AKO mice) and w...

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Pubblicato in:Int J Mol Sci
Autori principali: Takahashi, Akinori, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Ferwati, Sara, Kuba, Keiji, Yamamoto, Tadashi, Suzuki, Toru
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862216/
https://ncbi.nlm.nih.gov/pubmed/31652943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215274
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