The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

The biological significance of deadenylation in global gene expression is not fully understood. Here, we show that the CCR4–NOT deadenylase complex maintains expression of mRNAs, such as those encoding transcription factors, cell cycle regulators, DNA damage response–related proteins, and metabolic...

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Détails bibliographiques
Publié dans:Life Sci Alliance
Auteurs principaux: Takahashi, Akinori, Suzuki, Toru, Soeda, Shou, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Mohamed, Haytham Mohamed Aly, Yanagiya, Akiko, Abe, Takaya, Shigeta, Mayo, Furuta, Yasuhide, Kuba, Keiji, Yamamoto, Tadashi
Format: Artigo
Langue:Inglês
Publié: Life Science Alliance LLC 2020
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119370/
https://ncbi.nlm.nih.gov/pubmed/32238456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900494
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