The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

The biological significance of deadenylation in global gene expression is not fully understood. Here, we show that the CCR4–NOT deadenylase complex maintains expression of mRNAs, such as those encoding transcription factors, cell cycle regulators, DNA damage response–related proteins, and metabolic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Life Sci Alliance
Prif Awduron: Takahashi, Akinori, Suzuki, Toru, Soeda, Shou, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Mohamed, Haytham Mohamed Aly, Yanagiya, Akiko, Abe, Takaya, Shigeta, Mayo, Furuta, Yasuhide, Kuba, Keiji, Yamamoto, Tadashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Life Science Alliance LLC 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119370/
https://ncbi.nlm.nih.gov/pubmed/32238456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900494
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