The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation

The biological significance of deadenylation in global gene expression is not fully understood. Here, we show that the CCR4–NOT deadenylase complex maintains expression of mRNAs, such as those encoding transcription factors, cell cycle regulators, DNA damage response–related proteins, and metabolic...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Takahashi, Akinori, Suzuki, Toru, Soeda, Shou, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Mohamed, Haytham Mohamed Aly, Yanagiya, Akiko, Abe, Takaya, Shigeta, Mayo, Furuta, Yasuhide, Kuba, Keiji, Yamamoto, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119370/
https://ncbi.nlm.nih.gov/pubmed/32238456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900494
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