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The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

Shortening of poly(A) tails triggers mRNA degradation; hence, mRNA deadenylation regulates many biological events. In the present study, we generated mice lacking the Cnot1 gene, which encodes an essential scaffold subunit of the CCR4–NOT deadenylase complex in adipose tissues (Cnot1-AKO mice) and w...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Takahashi, Akinori, Takaoka, Shohei, Kobori, Shungo, Yamaguchi, Tomokazu, Ferwati, Sara, Kuba, Keiji, Yamamoto, Tadashi, Suzuki, Toru
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862216/
https://ncbi.nlm.nih.gov/pubmed/31652943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215274
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