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Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential
Many anticancer strategies rely on the promotion of apoptosis in cancer cells as a means to shrink tumors. Crucial for apoptotic function are executioner caspases, most notably caspase-3, that proteolyze a variety of proteins, inducing cell death. Paradoxically, overexpression of procaspase-3 (PC-3)...
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| Published in: | ACS Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858495/ https://ncbi.nlm.nih.gov/pubmed/31260254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00338 |
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