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Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics

[Image: see text] Conventional chemotherapeutics remain essential treatments for most cancers, but their combination with other anticancer drugs (including targeted therapeutics) is often complicated by unpredictable synergies and multiplicative toxicities. As cytotoxic anticancer chemotherapeutics...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Botham, Rachel C., Roth, Howard S., Book, Alison P., Roady, Patrick J., Fan, Timothy M., Hergenrother, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999974/
https://ncbi.nlm.nih.gov/pubmed/27610416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00165
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