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Leveraging peptide substrate libraries to design inhibitors of bacterial Lon protease
Lon is a widely-conserved housekeeping protease found in all domains of life. Bacterial Lon is involved in the recovery from various types of stress, including tolerance to fluoroquinolone antibiotics, and is linked to pathogenesis in a number of organisms. However, detailed functional studies of Lo...
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| Gepubliceerd in: | ACS Chem Biol |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858493/ https://ncbi.nlm.nih.gov/pubmed/31464417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00529 |
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