Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal

Purpose: Retinal organoids generated from human pluripotent stem cells exhibit considerable variability during differentiation. Our goals are to assess developmental maturity of the neural retina in vitro and design improved protocols based on objective criteria. Methods: We performed transcriptome...

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Bibliografski detalji
Izdano u:Mol Vis
Glavni autori: Kaya, Koray D., Chen, Holly Y., Brooks, Matthew J., Kelley, Ryan A., Shimada, Hiroko, Nagashima, Kunio, de Val, Natalia, Drinnan, Charles T., Gieser, Linn, Kruczek, Kamil, Erceg, Slaven, Li, Tiansen, Lukovic, Dunja, Adlakha, Yogita K., Welby, Emily, Swaroop, Anand
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2019
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Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857775/
https://ncbi.nlm.nih.gov/pubmed/31814692
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