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Accelerated Development of Rod Photoreceptors in Retinal Organoids Derived from Human Pluripotent Stem Cells by Supplementation with 9-cis Retinal

Human pluripotent stem cells (PSCs) can be differentiated into retinal organoids with proper neural layer organization, yet the protocols are technically challenging and time consuming. We have modified a widely used differentiation protocol by switching all-trans retinoic acid with 9-cis retinal to...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Kelley, Ryan A., Chen, Holly Y., Swaroop, Anand, Li, Tiansen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388645/
https://ncbi.nlm.nih.gov/pubmed/32728670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100033
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