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Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation

PURPOSE: The generation of three-dimensional (3D) organoids with optic cup–like structures from pluripotent stem cells has created opportunities for investigating mammalian retinal development in vitro. However, retinal organoids in culture do not completely reflect the developmental state and in vi...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Chen, Holly Yu, Kaya, Koray Dogan, Dong, Lijin, Swaroop, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017542/
https://ncbi.nlm.nih.gov/pubmed/27667917
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