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Three-dimensional retinal organoids from mouse pluripotent stem cells mimic in vivo development with enhanced stratification and rod photoreceptor differentiation

PURPOSE: The generation of three-dimensional (3D) organoids with optic cup–like structures from pluripotent stem cells has created opportunities for investigating mammalian retinal development in vitro. However, retinal organoids in culture do not completely reflect the developmental state and in vi...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Vis
Hauptverfasser: Chen, Holly Yu, Kaya, Koray Dogan, Dong, Lijin, Swaroop, Anand
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017542/
https://ncbi.nlm.nih.gov/pubmed/27667917
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