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Allosteric changes in HDM2 by the ATM phosphomimetic S395D mutation: implications on HDM2 function
Allosteric changes imposed by post-translational modifications regulate and differentiate the functions of proteins with intrinsic disorder regions. HDM2 is a hub protein with a large interactome and with different cellular functions. It is best known for its regulation of the p53 tumour suppressor....
Guardat en:
| Publicat a: | Biochem J |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6857739/ https://ncbi.nlm.nih.gov/pubmed/31652301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190687 |
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