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Dual function of MDM2 and MDMX toward the tumor suppressors p53 and RB
The orchestrated crosstalk between the retinoblastoma (RB) and p53 pathways contributes to preserving proper homeostasis within the cell. The deregulation of one or both pathways is a common factor in the development of most types of human cancer. The proto-oncoproteins MDMX and MDM2 are the main re...
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| Publicado no: | Genes Cancer |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115168/ https://ncbi.nlm.nih.gov/pubmed/28050229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/genesandcancer.120 |
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