Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial

Rationale: Population studies suggest improved sepsis outcomes with statins, but the results of randomized controlled trials in patients with sepsis and organ dysfunction in critical care settings have broadly been negative. In vitro data suggest that statins modulate age-related neutrophil function...

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Publicado en:Am J Respir Crit Care Med
Autores principales: Sapey, Elizabeth, Patel, Jaimin M., Greenwood, Hannah, Walton, Georgia M., Grudzinska, Frances, Parekh, Dhruv, Mahida, Rahul Y., Dancer, Rachel C. A., Lugg, Sebastian T., Howells, Philip A., Hazeldine, Jon, Newby, Paul, Scott, Aaron, Nightingale, Peter, Hill, Adam T., Thickett, David R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857486/
https://ncbi.nlm.nih.gov/pubmed/31206313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201812-2328OC
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