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Sepsis Induces a Dysregulated Neutrophil Phenotype That Is Associated with Increased Mortality

BACKGROUND: Neutrophil dysfunction in sepsis has been implicated in the pathogenesis of multiorgan failure; however, the role of neutrophil extracellular traps (NETs) remains uncertain. We aimed to determine the sequential changes in ex vivo NETosis and its relationship with mortality in patients wi...

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Bibliografiske detaljer
Udgivet i:Mediators Inflamm
Main Authors: Patel, Jaimin M., Sapey, Elizabeth, Parekh, Dhruv, Scott, Aaron, Dosanjh, Davinder, Gao, Fang, Thickett, David R.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925119/
https://ncbi.nlm.nih.gov/pubmed/29849488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4065362
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