Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial

Rationale: Population studies suggest improved sepsis outcomes with statins, but the results of randomized controlled trials in patients with sepsis and organ dysfunction in critical care settings have broadly been negative. In vitro data suggest that statins modulate age-related neutrophil function...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Sapey, Elizabeth, Patel, Jaimin M., Greenwood, Hannah, Walton, Georgia M., Grudzinska, Frances, Parekh, Dhruv, Mahida, Rahul Y., Dancer, Rachel C. A., Lugg, Sebastian T., Howells, Philip A., Hazeldine, Jon, Newby, Paul, Scott, Aaron, Nightingale, Peter, Hill, Adam T., Thickett, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857486/
https://ncbi.nlm.nih.gov/pubmed/31206313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201812-2328OC
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