Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin

Rationale: Dysregulated neutrophil functions with age and sepsis are described. Statins are associated with improved infection survival in some observational studies, but trials in critically ill patients have not shown benefit. Statins also alter neutrophil responses in vitro. Objectives: To assess...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Sapey, Elizabeth, Patel, Jaimin M., Greenwood, Hannah L., Walton, Georgia M., Hazeldine, Jon, Sadhra, Charendeep, Parekh, Dhruv, Dancer, Rachel C. A., Nightingale, Peter, Lord, Janet M., Thickett, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694832/
https://ncbi.nlm.nih.gov/pubmed/28657793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201704-0814OC
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