Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin

Rationale: Dysregulated neutrophil functions with age and sepsis are described. Statins are associated with improved infection survival in some observational studies, but trials in critically ill patients have not shown benefit. Statins also alter neutrophil responses in vitro. Objectives: To assess...

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Dades bibliogràfiques
Publicat a:Am J Respir Crit Care Med
Autors principals: Sapey, Elizabeth, Patel, Jaimin M., Greenwood, Hannah L., Walton, Georgia M., Hazeldine, Jon, Sadhra, Charendeep, Parekh, Dhruv, Dancer, Rachel C. A., Nightingale, Peter, Lord, Janet M., Thickett, David R.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694832/
https://ncbi.nlm.nih.gov/pubmed/28657793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201704-0814OC
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