Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin

Rationale: Dysregulated neutrophil functions with age and sepsis are described. Statins are associated with improved infection survival in some observational studies, but trials in critically ill patients have not shown benefit. Statins also alter neutrophil responses in vitro. Objectives: To assess...

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書目詳細資料
發表在:Am J Respir Crit Care Med
Main Authors: Sapey, Elizabeth, Patel, Jaimin M., Greenwood, Hannah L., Walton, Georgia M., Hazeldine, Jon, Sadhra, Charendeep, Parekh, Dhruv, Dancer, Rachel C. A., Nightingale, Peter, Lord, Janet M., Thickett, David R.
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2017
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694832/
https://ncbi.nlm.nih.gov/pubmed/28657793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201704-0814OC
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