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Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress

Clonal microbial populations are inherently heterogeneous, and this diversification is often considered as an adaptation strategy. In clinical infections, phenotypic diversity is found to be associated with drug tolerance, which in turn could evolve into genetic resistance. Mycobacterium tuberculosi...

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Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Manina, Giulia, Griego, Anna, Singh, Lalit Kumar, McKinney, John D, Dhar, Neeraj
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856624/
https://ncbi.nlm.nih.gov/pubmed/31583725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101876
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