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Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice
Tuberculosis (TB) is notoriously difficult to cure, requiring administration of multiple antibiotics for 6 mo or longer. Conventional anti-TB drugs inhibit biosynthetic processes involved in cell growth and division, such as DNA replication, RNA transcription, protein translation, and cell wall biog...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901468/ https://ncbi.nlm.nih.gov/pubmed/20566858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003219107 |
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