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Mycobacterium tuberculosis persistence mutants identified by screening in isoniazid-treated mice

Tuberculosis (TB) is notoriously difficult to cure, requiring administration of multiple antibiotics for 6 mo or longer. Conventional anti-TB drugs inhibit biosynthetic processes involved in cell growth and division, such as DNA replication, RNA transcription, protein translation, and cell wall biog...

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Main Authors: Dhar, Neeraj, McKinney, John D.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901468/
https://ncbi.nlm.nih.gov/pubmed/20566858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003219107
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