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Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress
Clonal microbial populations are inherently heterogeneous, and this diversification is often considered as an adaptation strategy. In clinical infections, phenotypic diversity is found to be associated with drug tolerance, which in turn could evolve into genetic resistance. Mycobacterium tuberculosi...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6856624/ https://ncbi.nlm.nih.gov/pubmed/31583725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101876 |
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