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Imaging of Tissue-specific and Temporal Activation of GPCR Signaling using DREADD Knock-In Mice
Engineered G-protein coupled receptors (DREADDs, designer receptors exclusively activated by designer drugs) are convenient tools for specific activation of GPCR signaling in many cell types. DREADDs have been utilized as research tools to study numerous cellular and physiologic processes, including...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6855306/ https://ncbi.nlm.nih.gov/pubmed/30969428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9121-1_21 |
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