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Knock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB Activity
The cAMP response element binding protein (CREB) is induced during fasting in the liver, where it stimulates transcription of rate-limiting gluconeogenic genes to maintain metabolic homeostasis. Adenoviral and transgenic CREB reporters have been used to monitor hepatic CREB activity non-invasively u...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940169/ https://ncbi.nlm.nih.gov/pubmed/27336479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158274 |
| Oznake: |
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