Knock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB Activity

The cAMP response element binding protein (CREB) is induced during fasting in the liver, where it stimulates transcription of rate-limiting gluconeogenic genes to maintain metabolic homeostasis. Adenoviral and transgenic CREB reporters have been used to monitor hepatic CREB activity non-invasively u...

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Bibliographic Details
Published in:PLoS One
Main Authors: Akhmedov, Dmitry, Rajendran, Kavitha, Mendoza-Rodriguez, Maria G., Berdeaux, Rebecca
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940169/
https://ncbi.nlm.nih.gov/pubmed/27336479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158274
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