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Imaging of Tissue-specific and Temporal Activation of GPCR Signaling using DREADD Knock-In Mice

Engineered G-protein coupled receptors (DREADDs, designer receptors exclusively activated by designer drugs) are convenient tools for specific activation of GPCR signaling in many cell types. DREADDs have been utilized as research tools to study numerous cellular and physiologic processes, including...

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Библиографические подробности
Опубликовано в: :Methods Mol Biol
Главные авторы: Akhmedov, Dmitry, Kirkby, Nicholas S., Mitchell, Jane A., Berdeaux, Rebecca
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855306/
https://ncbi.nlm.nih.gov/pubmed/30969428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9121-1_21
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