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Imaging of Tissue-specific and Temporal Activation of GPCR Signaling using DREADD Knock-In Mice

Engineered G-protein coupled receptors (DREADDs, designer receptors exclusively activated by designer drugs) are convenient tools for specific activation of GPCR signaling in many cell types. DREADDs have been utilized as research tools to study numerous cellular and physiologic processes, including...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Akhmedov, Dmitry, Kirkby, Nicholas S., Mitchell, Jane A., Berdeaux, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855306/
https://ncbi.nlm.nih.gov/pubmed/30969428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9121-1_21
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