Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders

Evidence from multiple laboratories has accumulated to show that mosaic neuronal aneuploidy and consequent apoptosis characterizes and may underlie neuronal loss in many neurodegenerative diseases, particularly Alzheimer’s disease and frontotemporal dementia. Furthermore, several neurodevelopmental...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Potter, Huntington, Chial, Heidi J., Caneus, Julbert, Elos, Mihret, Elder, Nina, Borysov, Sergiy, Granic, Antoneta
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855267/
https://ncbi.nlm.nih.gov/pubmed/31788001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01092
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