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Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer’s Disease
Trisomy 21 and the consequent extra copy of the amyloid precursor protein (APP) gene and increased beta-amyloid (Aβ) peptide production underlie the universal development of Alzheimer’s disease (AD) pathology and high risk of AD dementia in people with Down syndrome (DS). Trisomy 21 and other forms...
में बचाया:
| में प्रकाशित: | Curr Alzheimer Res |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570437/ https://ncbi.nlm.nih.gov/pubmed/26651340 |
| टैग : |
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