Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model

Acute lymphoblastic leukemia (ALL) develops in the bone marrow in the vicinity of stromal cells known to promote tumor development and treatment resistance. We previously showed that the cyclooxygenase (COX) inhibitor indomethacin prevents the ability of stromal cells to diminish p53-mediated killin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Adv
Egile Nagusiak: Richartz, Nina, Duthil, Eva, Ford, Anthony, Naderi, Elin Hallan, Bhagwat, Sampada, Gilljam, Karin M., Burman, Marta Maria, Ruud, Ellen, Blomhoff, Heidi Kiil, Skah, Seham
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2019
Gaiak:
Lymphoid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855122/
https://ncbi.nlm.nih.gov/pubmed/31698450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000473
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