Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model

Acute lymphoblastic leukemia (ALL) develops in the bone marrow in the vicinity of stromal cells known to promote tumor development and treatment resistance. We previously showed that the cyclooxygenase (COX) inhibitor indomethacin prevents the ability of stromal cells to diminish p53-mediated killin...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Richartz, Nina, Duthil, Eva, Ford, Anthony, Naderi, Elin Hallan, Bhagwat, Sampada, Gilljam, Karin M., Burman, Marta Maria, Ruud, Ellen, Blomhoff, Heidi Kiil, Skah, Seham
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855122/
https://ncbi.nlm.nih.gov/pubmed/31698450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000473
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