Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model

Acute lymphoblastic leukemia (ALL) develops in the bone marrow in the vicinity of stromal cells known to promote tumor development and treatment resistance. We previously showed that the cyclooxygenase (COX) inhibitor indomethacin prevents the ability of stromal cells to diminish p53-mediated killin...

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Bibliografische gegevens
Gepubliceerd in:Blood Adv
Hoofdauteurs: Richartz, Nina, Duthil, Eva, Ford, Anthony, Naderi, Elin Hallan, Bhagwat, Sampada, Gilljam, Karin M., Burman, Marta Maria, Ruud, Ellen, Blomhoff, Heidi Kiil, Skah, Seham
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2019
Onderwerpen:
Lymphoid Neoplasia
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855122/
https://ncbi.nlm.nih.gov/pubmed/31698450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000473
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