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Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model

Acute lymphoblastic leukemia (ALL) develops in the bone marrow in the vicinity of stromal cells known to promote tumor development and treatment resistance. We previously showed that the cyclooxygenase (COX) inhibitor indomethacin prevents the ability of stromal cells to diminish p53-mediated killin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Blood Adv
मुख्य लेखकों: Richartz, Nina, Duthil, Eva, Ford, Anthony, Naderi, Elin Hallan, Bhagwat, Sampada, Gilljam, Karin M., Burman, Marta Maria, Ruud, Ellen, Blomhoff, Heidi Kiil, Skah, Seham
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6855122/
https://ncbi.nlm.nih.gov/pubmed/31698450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000473
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